IDMembersPhysical
Score
Correlation
135PAT1 SNU66 LSM6 LSM7 LSM1 KEM1
PAT1 MRT1 Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p
SNU66 Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures
LSM6 Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
LSM7 Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
LSM1 SPB8 Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs
KEM1 DST2|RAR5|SEP1|SKI1|XRN1 Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance
IDMembers# IntsMean Score (FDR)Network
Between Scores
77YPT6 62.7112(.1%)
319VAM3 52.5396(.1%)
155RGP1 RIC1 82.7536(0.01%)
567SWC7 SWC5 SWC3 YAF9 ARP6 VPS71 SWR1 VPS72 46-4.821(0.01%)
715SPT21 63.5671(0.01%)
616SSF1 52.6729(.1%)
354HPC2 HIR3 HIR2 HIR1 ASF1 RAD53 32-4.909(0.01%)
393SKI8 SKI3 SKI2 YKL023W 20-3.486(0.01%)
347POL30 HYS2 POL32 161.2679(1%)
385LRP1 RRP6 122.2729(0.01%)
281THP1 SAC3 9-4.715(.1%)
205PFD1 PAC10 YKE2 GIM5 GIM4 GIM3 BUD27 380.6991(1%)
115GAL11 MED4 SSN2 SSN3 SIN4 SOH1 SSN8 ROX3 MED2 MED11 MED1 NUT1 PGD1 CSE2 MED8 SRB2 SRB8 83-2.928(0.01%)
163YCR076C PRE9 UMP1 161.081(1%)
418BIM1 6-6.835(0.01%)
360SUS1 5-8.613(0.01%)
65REI1 42.6106(1%)