IDMembersPhysical
Score
Correlation
274ELP3 ELP6 ELP4 IKI3 ELP2 IKI1
ELP3 HPA1|TOT3 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin
ELP6 HAP3|TOT6 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
ELP4 HAP1|TOT7 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
IKI3 ELP1|TOT1 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)
ELP2 TOT2 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
IKI1 ELP5|HAP2|TOT5 Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin
IDMembers# IntsMean Score (FDR)Network
Between Scores
216GET1 6-9.053(0.01%)
115GAL11 MED4 SSN2 SSN3 SIN4 SOH1 SSN8 ROX3 MED2 MED11 MED1 NUT1 PGD1 CSE2 MED8 SRB2 SRB8 82-1.544(0.01%)
627CIK1 63.0226(0.01%)
544APQ12 62.5418(.1%)
668PHO23 SAP30 RCO1 CTI6 UME1 UME6 RXT2 RXT3 SIN3 EAF3 DEP1 RPD3 SDS3 70-1.822(0.01%)
337GET2 6-7.412(0.01%)
641TAF7 TAF6 TAF5 TAF4 TAF1 SPT8 UBP8 HFI1 SGF29 SGF73 TAF13 TAF12 TAF9 NGG1 SPT3 SGF11 GCN5 74-1.194(.1%)
183VPS75 RTT109 112.2306(0.01%)
653SEC22 6-5.899(.1%)
71IRA2 62.8081(.1%)
205PFD1 PAC10 YKE2 GIM5 GIM4 GIM3 BUD27 36-2.001(.1%)
365VRP1 SLA1 8-5.249(.1%)
425MBP1 SWI4 SWI6 10-3.969(1%)