IDMembersPhysical
Score
Correlation
611SNT1 HST1 HOS4 HOS2 SET3 SIF2 CPR1
SNT1 Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein
HST1 NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance
HOS4 Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
HOS2 RTL1 Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity
SET3 Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains
SIF2 EMB1 WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
CPR1 CPH1|CYP1 Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A
IDMembers# IntsMean Score (FDR)Network
Between Scores
205PFD1 PAC10 YKE2 GIM5 GIM4 GIM3 BUD27 47-2.018(0.01%)
668PHO23 SAP30 RCO1 CTI6 UME1 UME6 RXT2 RXT3 SIN3 EAF3 DEP1 RPD3 SDS3 88-2.642(0.01%)
159PRI1 73.0567(0.01%)
715SPT21 72.1538(.1%)
567SWC7 SWC5 SWC3 YAF9 ARP6 VPS71 SWR1 VPS72 55-3.849(0.01%)
653SEC22 6-5.821(.1%)
544APQ12 6-5.072(1%)
155RGP1 RIC1 13-4.277(0.01%)
94RPN2 POL4 RPN6 UBP6 GSG1 ECM29 RPN13 RPN10 HEX3 SEM1 580.4912(1%)