IDMembersPhysical
Score
Correlation
641TAF7 TAF6 TAF5 TAF4 TAF1 SPT8 UBP8 HFI1 SGF29 SGF73 TAF13 TAF12 TAF9 NGG1 SPT3 SGF11 GCN5
TAF7 TAF67 TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation
TAF6 TAF60 Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4
TAF5 TAF90 Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
TAF4 MPT1|TAF48|TSG2 TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate
TAF1 TAF130|TAF145 TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression
SPT8 Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters
UBP8 Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B
HFI1 ADA1|GAN1|SRM12|SUP110 Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions
SGF29 SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex
SGF73 SCA7 73 kDa subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters
TAF13 FUN81|TAF19 TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors
TAF12 TAF61|TAF68 Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A
TAF9 TAF17 Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3
NGG1 ADA3|SWI7 Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex
SPT3 Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters
SGF11 Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation
GCN5 ADA4|SWI9 Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily
IDMembers# IntsMean Score (FDR)Network
Between Scores
205PFD1 PAC10 YKE2 GIM5 GIM4 GIM3 BUD27 1060.7101(0.01%)
668PHO23 SAP30 RCO1 CTI6 UME1 UME6 RXT2 RXT3 SIN3 EAF3 DEP1 RPD3 SDS3 184-0.835(.1%)
699MDM35 161.1161(1%)
424UBP3 BRE5 34-1.706(1%)
115GAL11 MED4 SSN2 SSN3 SIN4 SOH1 SSN8 ROX3 MED2 MED11 MED1 NUT1 PGD1 CSE2 MED8 SRB2 SRB8 159-0.907(.1%)
428SNF5 SNF11 SWI3 35-1.769(1%)
498CTF8 DCC1 32-1.898(1%)
274ELP3 ELP6 ELP4 IKI3 ELP2 IKI1 74-1.194(.1%)
567SWC7 SWC5 SWC3 YAF9 ARP6 VPS71 SWR1 VPS72 116-2.625(0.01%)
172SHP1 DOA1 34-2.055(.1%)