IDMembersPhysical
Score
Correlation
673CHD1 CKA1 CKA2 CDC73 PAF1 LEO1 CTR9 RTF1 CKB1 CKB2 POB3
CHD1 Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SILK complexes
CKA1 Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
CKA2 YOR29-12 Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases
CDC73 Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance
PAF1 RNAP II-associated protein; defines large complex biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme; required for full expression of a subset of cell cycle-regulated genes; homolog of human PD2/hPAF1
LEO1 Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation
CTR9 CDP1 Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats
RTF1 CSL3 Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance
CKB1 Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases
CKB2 Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases
POB3 Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure
IDMembers# IntsMean Score (FDR)Network
Between Scores
216GET1 9-4.750(.1%)
155RGP1 RIC1 16-3.349(1%)
624ELF1 11-3.154(1%)
36LGE1 BRE1 211.2673(0.01%)
552OPI3 11-3.549(1%)
77YPT6 11-4.251(.1%)
354HPC2 HIR3 HIR2 HIR1 ASF1 RAD53 59-2.403(0.01%)
653SEC22 9-4.941(.1%)
205PFD1 PAC10 YKE2 GIM5 GIM4 GIM3 BUD27 681.1937(0.01%)
567SWC7 SWC5 SWC3 YAF9 ARP6 VPS71 SWR1 VPS72 80-2.285(0.01%)
424UBP3 BRE5 21-2.810(1%)
521SAC1 9-4.189(.1%)